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Prophylactic small-dose oral amiodarone used in clients going through open-coronary heart surgery was perfectly tolerated and significantly decreased the incidence of postoperative atrial fibrillation, together with the size and price of hospitalization. Additionally, compared with class I or other course III antiarrhythmic agents, oral amiodarone was not affiliated with an elevated hazard of adverse activities, especially ventricular proarrhythmia.
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Using prophylactic oral amiodarone for at least a single 7 days right before elective coronary heart surgical procedures minimized the incidence of postoperative atrial fibrillation by close to 50 per cent, drastically reduced the size and overall expense of hospitalization, and minimized the volume of symptomatic episodes of atrial fibrillation transpiring after discharge.
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Failure to detect brief, asymptomatic episodes of atrial fibrillation or asymptomatic arrhythmias was unlikely to impact patient treatment or influence it adversely and does not detract with the scientific implications of this study.